The 45th Annual Meeting of the International Society for Heart and Lung Transplantation (ISHLT) 2025 will be held April 27-30, 2025, in Boston.The International Society for Heart and Lung Transplantation (ISHLT) Annual Meeting ISHLT is the world's largest gathering of researchers and practitioners dedicated to improving the lives of patients with end-stage heart and lung disease. The International Society for Heart and Lung Transplantation (ISHLT) is a nonprofit, multidisciplinary, professional organization dedicated to improving the care of patients with advanced heart and lung disease through transplantation, mechanical support, and innovative therapies through research, education, and advocacy. By organizing into 4 core practice areas focused on the treatment/disease of advanced heart failure and transplantation, advanced lung failure and transplantation, mechanical circulatory support, and pulmonary vascular disease (PAH and CTEPH) called Interdisciplinary Networks that leverage the value of our multidisciplinary approach to achieving our mission, this interdisciplinary focus is a unique aspect of the ISHLT and is a member and industry partner's primary value because it brings together all decision makers (surgeons, physicians, allied health professionals, and scientists) to address the management of advanced heart and lung disease.