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Medical research
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Metformin during pregnancy impacts offspring brain development, finds study

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C
New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma
Autophagy-tethering compounds may open new directions in targeted drug discovery

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting
Study eases concern at antipsychotics use in pregnancy

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o
CBD products don't ease pain and are potentially harmful, study finds

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm
FDA approves oral Duvyzat for Duchenne muscular dystrophy

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Medicare to cover Wegovy when patients also have heart disease

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A
Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their pos

Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their pos
Researchers pinpoint issue that could be hampering common chemotherapy drug

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche
Choosing over the counter drugs for COVID 19? It's complicated

Choosing over the counter drugs for COVID 19? It's complicated

byFlorida Atlantic UniversityResearchers take a closer look at both the potential benefits and risks of acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs)—such as ibuprofen, as well a

Choosing over the counter drugs for COVID 19? It's complicated

byFlorida Atlantic UniversityResearchers take a closer look at both the potential benefits and risks of acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs)—such as ibuprofen, as well a
Mimicking exercise with a pill

Mimicking exercise with a pill

byAmerican Chemical SocietyCredit: Unsplash/CC0 Public DomainDoctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exe

Mimicking exercise with a pill

byAmerican Chemical SocietyCredit: Unsplash/CC0 Public DomainDoctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exe