New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on: March 13,2024 7

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on:March 13,2024 7

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on: May 08,2024 5

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on:May 08,2024 5

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on: March 30,2024 3

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on:March 30,2024 3

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on: April 06,2024 0

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on:April 06,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on: October 22,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on:October 22,2024 0

What’s that smell — and how’d you know?

Updated on: October 22,2024 0

What’s that smell — and how’d you know?

Updated on:October 22,2024 0

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Updated on: December 04,2024 0

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Updated on:December 04,2024 0

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on: March 25,2024 4

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on:March 25,2024 4

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on: August 26,2024 0

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on:August 26,2024 0

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on: March 25,2024 11

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on:March 25,2024 11

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on: October 28,2024 0

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on:October 28,2024 0

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on: March 27,2024 0

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on:March 27,2024 0