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Medical research
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Gene therapy gets a turbo boost from researchers

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease
Serious flu damage prevented by compound that blocks unnecessary cell death

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the
Chemical and computational advances enable 2D proteomics measurements of spatial signals

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod
New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri
Key mechanism governing bone marrow stem cells opens door to new therapies

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
Wound healing checked in real time with electronic suture

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P
Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti