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Perfecting 3D-printed blood vessels with pores

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman
Bridging diet, microbes, and metabolism: Implications for metabolic disorders

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i
Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide
Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb
Insights into epigenetics: The humanized FKBP5 mouse as a model organism

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de
Researcher identifies key mechanism in Parkinson's disease

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec
Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic
Study finds embryos in hungry mouse moms postpone development

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,
Liver fibrosis 'off switch' discovered in mice

Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi

Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi