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Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

byUniversity of Texas M. D. Anderson Cancer CenterKaty Rezvani, M.D., Ph.D., working in her laboratory. Credit: MD Anderson Cancer CenterResearchers at The University of Texas MD Anderson Cancer

Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

byUniversity of Texas M. D. Anderson Cancer CenterKaty Rezvani, M.D., Ph.D., working in her laboratory. Credit: MD Anderson Cancer CenterResearchers at The University of Texas MD Anderson Cancer
New weight-loss drug Zepbound is now available, company says

New weight-loss drug Zepbound is now available, company says

by Robin FosterThe newly approved weight-loss medication known as Zepbound is now available for patients to take, drug maker Eli Lilly announced Tuesday."Today opens another chapter for adults li

New weight-loss drug Zepbound is now available, company says

by Robin FosterThe newly approved weight-loss medication known as Zepbound is now available for patients to take, drug maker Eli Lilly announced Tuesday."Today opens another chapter for adults li
Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i
A breath of fresh air keeps drug-producing cells alive longer

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a
Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps
Scientists develop tunable organic active neural probe enabling near-sensor signal processing

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li
The double-edge sword of CRISPR application for in vivo studies

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi
Exploring complement system response to adeno-associated virus vector gene therapy

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra
Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous