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Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th
New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Coronary sinus reducer relieves angina, but how it works remains unclear

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection
World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common
Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a
Human cells building 'molecular highways' captured for first time

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the
Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

by Alvin Powell, Harvard GazetteCredit: Unsplash/CC0 Public DomainSome health care professionals are growing concerned that amid the recent rush for the new highly effective, anti-obesity medications,

Researchers call for makers of new anti-obesity drugs to study results of body composition in addition to weight loss

by Alvin Powell, Harvard GazetteCredit: Unsplash/CC0 Public DomainSome health care professionals are growing concerned that amid the recent rush for the new highly effective, anti-obesity medications,
Aspirin cuts liver fat in clinical trial

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an
How to make mRNA therapeutics safe from the start

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern
New wearable patch measures trace perspiration during activity and rest

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear