PNAS | AlphaFold2 combined with supercomputing accelerates biophysical discoveries

The authors deployed APACE on the Delta and Polaris supercomputers and quantified its performance in accurate protein structure prediction using four typical proteins (6AWO, 6OAN, 7MEZ, and 6D6U). Utilizing up to 300 combinations distributed across 200 NV

Updated on: September 21,2024 0

PNAS | AlphaFold2 combined with supercomputing accelerates biophysical discoveries

The authors deployed APACE on the Delta and Polaris supercomputers and quantified its performance in accurate protein structure prediction using four typical proteins (6AWO, 6OAN, 7MEZ, and 6D6U). Utilizing up to 300 combinations distributed across 200 NV

Updated on:September 21,2024 0

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on: April 30,2024 0

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on:April 30,2024 0

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b

Updated on: January 04,2024 12

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b

Updated on:January 04,2024 12

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on: March 28,2024 0

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on:March 28,2024 0

New tool unifies single-cell data for the global research community

by Rachael Smith,Wellcome Trust Sanger InstituteGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.11.026A new methodology that allows for the categorization and organiz

Updated on: December 26,2023 12

New tool unifies single-cell data for the global research community

by Rachael Smith,Wellcome Trust Sanger InstituteGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.11.026A new methodology that allows for the categorization and organiz

Updated on:December 26,2023 12

Damaged nerve cells communicate with stem cells

Nerve cells damaged in diseases such as multiple sclerosis (MS), 'talk' to stem cells in the same way that they communicate with other nerve cells, calling out for 'first aid', accordi

Updated on: November 02,2023 10

Damaged nerve cells communicate with stem cells

Nerve cells damaged in diseases such as multiple sclerosis (MS), 'talk' to stem cells in the same way that they communicate with other nerve cells, calling out for 'first aid', accordi

Updated on:November 02,2023 10

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on: April 02,2024 11

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Updated on:April 02,2024 11

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on: May 05,2024 17

Natural products used in Ayurvedic treatments alleviate symptoms of depression in fruit flies

by Kathrin Voigt,Johannes Gutenberg University MainzThe level of motivation of the fruit fly Drosophila can be deduced on the basis of whether it attempts to climb over gaps it encounters when w

Updated on:May 05,2024 17

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-

Updated on: January 04,2024 12

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-

Updated on:January 04,2024 12

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

Updated on: March 21,2024 19

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

Updated on:March 21,2024 19

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend

Updated on: March 20,2024 16

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend

Updated on:March 20,2024 16