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Medical research
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UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha
New study lists potentially dangerous drugs in Australian health care

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi
A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and
Drug candidate granted FDA orphan drug status for pancreatic cancer

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug
Who benefits from direct-to-consumer pharmaceutical advertising?

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend
Study finds tafenoquine is a cost-effective treatment option for malaria

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),
Scientists code ChatGPT to design new medicine

Scientists code ChatGPT to design new medicine

by Chapman UniversityGraphical abstract. Credit:Pharmaceuticals(2024). DOI: 10.3390/ph17020161Generative artificial intelligence platforms, from ChatGPT to Midjourney, grabbed headlin

Scientists code ChatGPT to design new medicine

by Chapman UniversityGraphical abstract. Credit:Pharmaceuticals(2024). DOI: 10.3390/ph17020161Generative artificial intelligence platforms, from ChatGPT to Midjourney, grabbed headlin
FDA approves Winrevair for pulmonary arterial hypertension in adults

FDA approves Winrevair for pulmonary arterial hypertension in adults

by Lori SolomonThe U.S. Food and Drug Administration has approved Winrevair (sotatercept-csrk) as an injectable treatment for pulmonary arterial hypertension (PAH) in adults.The FDA previously granted

FDA approves Winrevair for pulmonary arterial hypertension in adults

by Lori SolomonThe U.S. Food and Drug Administration has approved Winrevair (sotatercept-csrk) as an injectable treatment for pulmonary arterial hypertension (PAH) in adults.The FDA previously granted
Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind
Anesthesia technology precisely controls unconsciousness in animal tests

Anesthesia technology precisely controls unconsciousness in animal tests

byMassachusetts Institute of TechnologySchematic of the propofol-based CLAD system for control of unconsciousness in an NHP. The user sets the target level of the marker of unconsciousness (MOU)

Anesthesia technology precisely controls unconsciousness in animal tests

byMassachusetts Institute of TechnologySchematic of the propofol-based CLAD system for control of unconsciousness in an NHP. The user sets the target level of the marker of unconsciousness (MOU)
Dos and don'ts developed for direct oral anticoagulants

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are