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Allergy&Clinical immunology
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How T cells amplify signals: New study reveals key molecular switch

How T cells amplify signals: New study reveals key molecular switch

byDelthia Ricks, Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDSignaling is fundamental to how cells

How T cells amplify signals: New study reveals key molecular switch

byDelthia Ricks, Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDSignaling is fundamental to how cells
FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

byUniversity of California, Los AngelesUCLA's Dr. Donald Kohn with Marley Gaskins and her mother, Tamara Hogue. Marley was the first patient to enroll in the LAD-l clinical trial in 2019. Credit:

FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

byUniversity of California, Los AngelesUCLA's Dr. Donald Kohn with Marley Gaskins and her mother, Tamara Hogue. Marley was the first patient to enroll in the LAD-l clinical trial in 2019. Credit:
Algae-derived sugars show anti-inflammatory effects and support skin repair

Algae-derived sugars show anti-inflammatory effects and support skin repair

byEstonian Research CouncilAmal D. Premarathna. Credit: Amal D. PremarathnaChronic wounds affect approximately 2% of the population in developed countries. Existing treatments are expensive and may ca

Algae-derived sugars show anti-inflammatory effects and support skin repair

byEstonian Research CouncilAmal D. Premarathna. Credit: Amal D. PremarathnaChronic wounds affect approximately 2% of the population in developed countries. Existing treatments are expensive and may ca
Study finds why asthma drugs help some children but not others

Study finds why asthma drugs help some children but not others

by Jackie Maupin,Indiana UniversityCredit: Pixabay/CC0 Public DomainIndiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for

Study finds why asthma drugs help some children but not others

by Jackie Maupin,Indiana UniversityCredit: Pixabay/CC0 Public DomainIndiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for
Persistent inflammation in older adults tied to GDF3 protein signaling

Persistent inflammation in older adults tied to GDF3 protein signaling

by Alex Smith,University of Minnesota Medical SchoolGdf3 promotes SMAD-regulated genes via altered chromatin accessibility in ATMs. Credit:Nature Aging(2025). DOI: 10.1038/s43587-025-01034-6As people

Persistent inflammation in older adults tied to GDF3 protein signaling

by Alex Smith,University of Minnesota Medical SchoolGdf3 promotes SMAD-regulated genes via altered chromatin accessibility in ATMs. Credit:Nature Aging(2025). DOI: 10.1038/s43587-025-01034-6As people
Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

by Elana GotkineFor patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a studypublishedonli

Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

by Elana GotkineFor patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a studypublishedonli
What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

byMax Delbrück Center for Molecular MedicineT stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, bot

What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

byMax Delbrück Center for Molecular MedicineT stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, bot
Soil bacteria and fungi emerge as top predictors of childhood allergic disease

Soil bacteria and fungi emerge as top predictors of childhood allergic disease

byAmerican Geophysical UnionCredit: Pixabay/CC0 Public DomainThe unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic diseas

Soil bacteria and fungi emerge as top predictors of childhood allergic disease

byAmerican Geophysical UnionCredit: Pixabay/CC0 Public DomainThe unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic diseas
Most parents are aware of early peanut introduction guidelines—but confused about the details

Most parents are aware of early peanut introduction guidelines—but confused about the details

byAnn & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainFeeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new st

Most parents are aware of early peanut introduction guidelines—but confused about the details

byAnn & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainFeeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new st
Liver cell reprogramming boosts T cell function in aging immune systems

Liver cell reprogramming boosts T cell function in aging immune systems

byMassachusetts Institute of TechnologyCredit: CC0 Public DomainAs people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, mak

Liver cell reprogramming boosts T cell function in aging immune systems

byMassachusetts Institute of TechnologyCredit: CC0 Public DomainAs people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, mak