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Breakthroughs
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One in five US cancer patients join in medical research

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t
Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or
Examining the potential of the common bovine as a potential therapeutic research model

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Ehrapy: A new open-source tool for analyzing complex health data

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t
Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR
Researchers identify peptides produced by the proteasome that degrade damaged proteins

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo
Danish study could pave the way for better diagnosis of rare genetic diseases

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o
Rapid drug test to provide patients with better care

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p
Pancreas cells in people who have died show significant signs of stress

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This
Research provides further evidence that epigenetic changes can cause type 2 diabetes

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc
How aging affects stem cells: A fly's tale

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key