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Breakthroughs
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Urine test halves painful procedures in bladder cancer follow up, new trial shows

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p
Familial Alzheimer's disease transferred via bone marrow transplant in mice

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr
Review paper unveils the potential of suppressor tRNA in gene therapy

Review paper unveils the potential of suppressor tRNA in gene therapy

byScience China PressCredit: Science China PressA review article provides a comprehensive overview of the biological mechanisms of suppressor tRNA, traces the development history of related rese

Review paper unveils the potential of suppressor tRNA in gene therapy

byScience China PressCredit: Science China PressA review article provides a comprehensive overview of the biological mechanisms of suppressor tRNA, traces the development history of related rese
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i
Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set
Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec
Danish study could pave the way for better diagnosis of rare genetic diseases

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o
The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
Research uncovers mechanism behind stubborn memories

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar
Researchers are using RNA in a new approach to fight HIV

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur