Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on: March 30,2024

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on:March 30,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on: March 30,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on:March 30,2024

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39

Updated on: April 27,2024

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39

Updated on:April 27,2024

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on: March 25,2024

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on:March 25,2024

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event

Updated on: March 13,2024

Scientists identify mutations that cause inherited kidney disease

byAtrium Health Wake Forest BaptistCredit:Kidney International(2023). DOI: 10.1016/j.kint.2023.11.021Genetic changes or mutations can cause hereditary kidney disease, which can event

Updated on:March 13,2024

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on: March 28,2024

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on:March 28,2024

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Updated on: April 06,2024

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Updated on:April 06,2024

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on: April 28,2024

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on:April 28,2024

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on: January 09,2024

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on:January 09,2024

Repurposed drug shows promise against endometriosis-related pain in animal model

byNational Institutes of HealthCredit: Pixabay/CC0 Public DomainFenoprofen, a nonsteroidal anti-inflammatory drug (NSAID), successfully alleviated pain and inflammation in a rodent model of endo

Updated on: March 28,2024

Repurposed drug shows promise against endometriosis-related pain in animal model

byNational Institutes of HealthCredit: Pixabay/CC0 Public DomainFenoprofen, a nonsteroidal anti-inflammatory drug (NSAID), successfully alleviated pain and inflammation in a rodent model of endo

Updated on:March 28,2024

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Updated on: April 28,2024

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Updated on:April 28,2024

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on: January 26,2024

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on:January 26,2024