Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024 0

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024 0

Exercise and Liraglutide: Effects on Weight Loss and Bone Health

This article delves into a study that investigates the effects of exercise, liraglutide, and their combination on weight loss and bone mineral density (BMD) in individuals with obesity.

Updated on: July 24,2024 0

Exercise and Liraglutide: Effects on Weight Loss and Bone Health

This article delves into a study that investigates the effects of exercise, liraglutide, and their combination on weight loss and bone mineral density (BMD) in individuals with obesity.

Updated on:July 24,2024 0

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024 16

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024 16

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on: February 05,2024 11

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on:February 05,2024 11

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on: March 28,2024 0

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on:March 28,2024 0

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Updated on: March 27,2024 4

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Updated on:March 27,2024 4

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on: April 28,2024 0

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on:April 28,2024 0

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model

Updated on: March 27,2024 0

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model

Updated on:March 27,2024 0

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Updated on: March 27,2024 0

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Updated on:March 27,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on: April 28,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on:April 28,2024 0

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from

Updated on: March 15,2024 5

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from

Updated on:March 15,2024 5

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for

Updated on: October 22,2024 0

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for

Updated on:October 22,2024 0