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Breakthroughs
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Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University
Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog
Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R
Study looks at ways to predict when a migraine attack will occur

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug
Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari
Study of usefulness of lockdowns during epidemics identifies alternate solution

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va
Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o
Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Medicare to cover Wegovy when patients also have heart disease

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A
Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.