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The fate of drug discovery in academia: Why is it so difficult?

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate
Combined antibiotics more effective against Lyme disease: Study

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p
Research team investigates difference between baby formula and human milk's effect on intestinal growth

Research team investigates difference between baby formula and human milk's effect on intestinal growth

by Alexa Tomassi,Yale School of MedicineCredit: Unsplash/CC0 Public DomainAn articlepublished inGastro Hep Advancesby a team of Yale researchers and led by Lauren Smith, MD, ho

Research team investigates difference between baby formula and human milk's effect on intestinal growth

by Alexa Tomassi,Yale School of MedicineCredit: Unsplash/CC0 Public DomainAn articlepublished inGastro Hep Advancesby a team of Yale researchers and led by Lauren Smith, MD, ho
Drug combo marks advance against bladder cancer

Drug combo marks advance against bladder cancer

by Ernie MundellA cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show.Patients who took a combo of meds called EV+P—

Drug combo marks advance against bladder cancer

by Ernie MundellA cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show.Patients who took a combo of meds called EV+P—
Study finds new treatment makes patients with life-threatening muscle weakness stronger

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas
Drug shows promise for slowing progression of rare, painful genetic disease

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce
New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit

New study suggests enhanced mitochondrial fusion fuels nerve cell function and plasticity

by University of CologneThe picture shows neurons (magenta) born in the adult mouse hippocampus. Nuclei are stained cyan. The extending dendrites are important sites where mechanisms of plasticit
Researchers race to develop Paxlovid replacement

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor
Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc
Researchers develop mixture of compounds to help preserve organs before transplantation

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs
New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs
Green tea may help mitigate harm from hookah smoking, mouse study suggests

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h