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Breakthroughs
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New antibiotic slays deadly superbug in early trial

New antibiotic slays deadly superbug in early trial

by Robin FosterResearchers report that a new type of antibiotic has proved its mettle against a deadly superbug.Acinetobacter baumannii, abacteriathat goes by the nickname CRAB when it bec

New antibiotic slays deadly superbug in early trial

by Robin FosterResearchers report that a new type of antibiotic has proved its mettle against a deadly superbug.Acinetobacter baumannii, abacteriathat goes by the nickname CRAB when it bec
These programs put unused prescription drugs in the hands of patients in need

These programs put unused prescription drugs in the hands of patients in need

by Kate Ruder, KFF Health NewsCredit: Pixabay/CC0 Public DomainOn a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs

These programs put unused prescription drugs in the hands of patients in need

by Kate Ruder, KFF Health NewsCredit: Pixabay/CC0 Public DomainOn a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs
Gene therapy gets a turbo boost from researchers

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease
Study finds Paxlovid treatment does not reduce risk of long COVID

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that
Long-distance and low-attenuation magnetic energy focusing technology for deep-tissue wireless powering

Long-distance and low-attenuation magnetic energy focusing technology for deep-tissue wireless powering

by Science China Press(a1) System design of the ULFMEF developed for wireless charging of implantable electronic devices, where the ULFMEF system consisted of an IMER and an EMET. (a2) Schematic

Long-distance and low-attenuation magnetic energy focusing technology for deep-tissue wireless powering

by Science China Press(a1) System design of the ULFMEF developed for wireless charging of implantable electronic devices, where the ULFMEF system consisted of an IMER and an EMET. (a2) Schematic
Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis
Researchers develop a new toolkit of fruit flies to study Zika virus

Researchers develop a new toolkit of fruit flies to study Zika virus

FEBRUARY 28, 2024byTexas Children's HospitalZIKV proteins cause scorable phenotypes upon overexpression in Drosophila. (A) Graphical diagram of the Zika virus (ZIKV) polyprotein, which conta

Researchers develop a new toolkit of fruit flies to study Zika virus

FEBRUARY 28, 2024byTexas Children's HospitalZIKV proteins cause scorable phenotypes upon overexpression in Drosophila. (A) Graphical diagram of the Zika virus (ZIKV) polyprotein, which conta
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
Study confirms how RNA chemical modifications benefit HIV-1

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate
Researchers develop framework to identify molecules responsible for chemotherapy resistance

Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr

Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr
Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley
A new vision for AAV-delivered gene therapies

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo