Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on: January 26,2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on:January 26,2024

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on: January 26,2024

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on:January 26,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on: January 02,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on:January 02,2024

Researchers develop novel method to improve disease prediction across diverse ancestries

byThe Mount Sinai HospitalBridgePRS improves prediction of African ancestry individuals in the New York BioMe cohort. Credit: Icahn School of Medicine at Mount SinaiA team of scientists from Ica

Updated on: December 28,2023

Researchers develop novel method to improve disease prediction across diverse ancestries

byThe Mount Sinai HospitalBridgePRS improves prediction of African ancestry individuals in the New York BioMe cohort. Credit: Icahn School of Medicine at Mount SinaiA team of scientists from Ica

Updated on:December 28,2023

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on: March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on:March 28,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024

Rodents may see moving objects in a way similar to primates, visual cortex study suggests

byInternational School of Advanced Studies (SISSA)To accurately perceive the direction of moving objects, rats could exploit a small but very useful cluster of visual neurons, which seem to work

Updated on: January 10,2024

Rodents may see moving objects in a way similar to primates, visual cortex study suggests

byInternational School of Advanced Studies (SISSA)To accurately perceive the direction of moving objects, rats could exploit a small but very useful cluster of visual neurons, which seem to work

Updated on:January 10,2024

Study describes five cutting-edge advances in biomedical engineering

FEBRUARY 27, 2024by Azeem Zeekrya,Mass General BrighamCredit: Unsplash/CC0 Public DomainIEEE, the world's largest technical professional organization dedicated to advancing technology for hu

Updated on: March 28,2024

Study describes five cutting-edge advances in biomedical engineering

FEBRUARY 27, 2024by Azeem Zeekrya,Mass General BrighamCredit: Unsplash/CC0 Public DomainIEEE, the world's largest technical professional organization dedicated to advancing technology for hu

Updated on:March 28,2024

FDA looking into new risks with popular weight-loss drugs

by Robin FosterThe U.S. Food and Drug Administration is investigating reports of additional dangers linked to several wildly popular weight-loss drugs.In aquarterly reportissued this week,

Updated on: January 26,2024

FDA looking into new risks with popular weight-loss drugs

by Robin FosterThe U.S. Food and Drug Administration is investigating reports of additional dangers linked to several wildly popular weight-loss drugs.In aquarterly reportissued this week,

Updated on:January 26,2024

Researchers discover novel drug candidate to combat fatty liver disease

by Gwangju Institute of Science and TechnologyResearchers discovered a compound 11c, a peripheral 5HT2A antagonist, exhibits promising efficacy against metabolic dysfunction-associated steatohepa

Updated on: April 06,2024

Researchers discover novel drug candidate to combat fatty liver disease

by Gwangju Institute of Science and TechnologyResearchers discovered a compound 11c, a peripheral 5HT2A antagonist, exhibits promising efficacy against metabolic dysfunction-associated steatohepa

Updated on:April 06,2024

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on: January 09,2024

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on:January 09,2024

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on: April 28,2024

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on:April 28,2024