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Breakthroughs
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Predicting correct dosage may improve success of drug repurposing

Predicting correct dosage may improve success of drug repurposing

by Sarah Small,Pennsylvania State UniversityCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a leng

Predicting correct dosage may improve success of drug repurposing

by Sarah Small,Pennsylvania State UniversityCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a leng
From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the
Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at
Magic mushrooms can treat medication-resistant depression—but are they safe?

Magic mushrooms can treat medication-resistant depression—but are they safe?

by Leigh Hataway,University of GeorgiaCredit: CC0 Public DomainNew research suggests psilocybin has similar side effects to traditional antidepressants. Commonly referred to as "magic mushr

Magic mushrooms can treat medication-resistant depression—but are they safe?

by Leigh Hataway,University of GeorgiaCredit: CC0 Public DomainNew research suggests psilocybin has similar side effects to traditional antidepressants. Commonly referred to as "magic mushr
ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28
A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and
Scientists discover surprise anticancer properties of common lab molecule

Scientists discover surprise anticancer properties of common lab molecule

by UNC HealthIncorporation of thymidine analogs into the human genome and removal of EdU by nucleotide excision repair. (A) Chemical structure of thymidine analogs used in this study. (B) Slot blot as

Scientists discover surprise anticancer properties of common lab molecule

by UNC HealthIncorporation of thymidine analogs into the human genome and removal of EdU by nucleotide excision repair. (A) Chemical structure of thymidine analogs used in this study. (B) Slot blot as
Urine biomarkers can outperform serum biomarkers in certain diseases

Urine biomarkers can outperform serum biomarkers in certain diseases

by KeAi Communications Co.Urine biomarkers can outperform serum biomarkers in certain diseases. Credit: Xue C, et al.In recent decades, the emphasis of biomarker research has centered around blood-bas

Urine biomarkers can outperform serum biomarkers in certain diseases

by KeAi Communications Co.Urine biomarkers can outperform serum biomarkers in certain diseases. Credit: Xue C, et al.In recent decades, the emphasis of biomarker research has centered around blood-bas
Announcement of the 2024 Nobel Prize in Chemistry

Announcement of the 2024 Nobel Prize in Chemistry

The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2024 with one half to David Baker, University of Washington, Seattle, WA, USA, “for computational protein design” and the other half jointly to Demis Hassabis, Google

Announcement of the 2024 Nobel Prize in Chemistry

The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2024 with one half to David Baker, University of Washington, Seattle, WA, USA, “for computational protein design” and the other half jointly to Demis Hassabis, Google
Who benefits from direct-to-consumer pharmaceutical advertising?

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend