Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on: January 26,2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on:January 26,2024

What if a virus could reverse antibiotic resistance?

Updated on: October 08,2024

What if a virus could reverse antibiotic resistance?

Updated on:October 08,2024

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on: January 26,2024

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on:January 26,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024

ASH: Daratumumab beneficial for patients with multiple myeloma

by Elana GotkineFor transplantation-eligible patients with newly diagnosed multiple myeloma, the addition of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone inductio

Updated on: January 26,2024

ASH: Daratumumab beneficial for patients with multiple myeloma

by Elana GotkineFor transplantation-eligible patients with newly diagnosed multiple myeloma, the addition of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone inductio

Updated on:January 26,2024

Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on: April 06,2024

Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on:April 06,2024

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on: January 02,2024

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on:January 02,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on: June 01,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on:June 01,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on: April 06,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on:April 06,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024