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Breakthroughs
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Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog
Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University
Researchers develop new tool to aid processing of spatial transcriptomic data

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers
Raspberry Pi-based system accurate for detecting facial palsy

Raspberry Pi-based system accurate for detecting facial palsy

DECEMBER 31, 2023by Elana GotkineA Raspberry Pi device with a digital camera and a deep learning algorithm can detect facial palsy (FP) with high accuracy, according to a study recently published in&n

Raspberry Pi-based system accurate for detecting facial palsy

DECEMBER 31, 2023by Elana GotkineA Raspberry Pi device with a digital camera and a deep learning algorithm can detect facial palsy (FP) with high accuracy, according to a study recently published in&n
Scientists develop an agent capable of selectively inhibiting the body's stress response

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N
RSV hospitalizations linked to considerable burden in adults

RSV hospitalizations linked to considerable burden in adults

by Elana GotkineRespiratory syncytial virus (RSV) is associated with a considerable burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to

RSV hospitalizations linked to considerable burden in adults

by Elana GotkineRespiratory syncytial virus (RSV) is associated with a considerable burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to
Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit
Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag
Super permeable wearable electronics developed for stable, long-term biosignal monitoring

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr