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Adding diversity to your research process: A new system

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N
Meningitis may have a much greater impact on child mortality than previously thought

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.
Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari
Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection
Mature 'lab grown' neurons hold promise for neurodegenerative disease

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours
Better cancer trials could be around the corner

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp
Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Analysis of research grants pipeline illustrates systematic disadvantages

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr