Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Updated on: December 03,2024

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Updated on:December 03,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on: November 22,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on:November 22,2024

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on: March 30,2024

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on:March 30,2024

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Updated on: March 30,2024

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Updated on:March 30,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on: March 13,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on:March 13,2024

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Updated on: March 30,2024

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Updated on:March 30,2024

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on: March 25,2024

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on:March 25,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on: March 30,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on:March 30,2024

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on: March 25,2024

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on:March 25,2024

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on: March 25,2024

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on:March 25,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on: October 02,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on:October 02,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024