Researchers find cold-activated brown fat asks for more sugar via signaling RNAkines

by Nanjing University School of Life SciencesBAT stimulates hepatic gluconeogenesis upon cold exposure.a–jEight-week-old male C57BL6/J mice were placed in RT (25 °C) or cold (4 °C) for 72 

Updated on: January 19,2024

Researchers find cold-activated brown fat asks for more sugar via signaling RNAkines

by Nanjing University School of Life SciencesBAT stimulates hepatic gluconeogenesis upon cold exposure.a–jEight-week-old male C57BL6/J mice were placed in RT (25 °C) or cold (4 °C) for 72 

Updated on:January 19,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on: March 14,2024

Shifting focus: Investigators describe changes to pancreatic β cells at onset of type 1 diabetes

by Joslin Diabetes CenterIn vivo AAV8-mediated overexpression of Mettl3 in NOD mouse β-cells delays T1D progression. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01368-0A

Updated on:March 14,2024

Popular weight-loss drugs show promise in reducing kidney disease complications and mortality

byUTSouthwestern Medical CenterCredit: Pixabay/CC0 Public DomainA well-known class of drugs used to manage type 2 diabetes and control weight could offer hope for patients who also struggl

Updated on: February 18,2025

Popular weight-loss drugs show promise in reducing kidney disease complications and mortality

byUTSouthwestern Medical CenterCredit: Pixabay/CC0 Public DomainA well-known class of drugs used to manage type 2 diabetes and control weight could offer hope for patients who also struggl

Updated on:February 18,2025

Resistant starch supplement found to reduce liver triglycerides in people with fatty liver disease

byCell PressCredit: Pixabay/CC0 Public DomainResistant starch is a non-digestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive e

Updated on: January 19,2024

Resistant starch supplement found to reduce liver triglycerides in people with fatty liver disease

byCell PressCredit: Pixabay/CC0 Public DomainResistant starch is a non-digestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive e

Updated on:January 19,2024

Does microdosing Ozempic work? What experts are saying about the diabetes drug also used for weight loss

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Markus Winkler from PexelsThe high price and side effects of Ozempic, the blockbuster diabetes drug also used off label for weight los

Updated on: November 07,2024

Does microdosing Ozempic work? What experts are saying about the diabetes drug also used for weight loss

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Markus Winkler from PexelsThe high price and side effects of Ozempic, the blockbuster diabetes drug also used off label for weight los

Updated on:November 07,2024

Obesity, but not poor diet and inactivity, linked to higher risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainA large study that followed more than one million women for nearly two decades has found that obesity in midlife is linked to a greater ri

Updated on: June 01,2024

Obesity, but not poor diet and inactivity, linked to higher risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainA large study that followed more than one million women for nearly two decades has found that obesity in midlife is linked to a greater ri

Updated on:June 01,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on: January 18,2024

Study reveals the role of ERRγ in the regulation of FGF23 gene expression following acute liver injury

by TranSpreadCCl4-induced acute liver injury increases FGF23 gene expression and secretion in mouse liver through ERRγ. (A, B) Quantitative PCR analysis of total RNA obtained from the livers of mice i

Updated on:January 18,2024

Higher cortisol levels may help predict risk of people developing depression in the future

by Trinity College DublinBall-and-stick model of the cortisol (hydrocortisone) molecule. Credit: Public DomainHigher levels of the stress hormone cortisol may increase the risk of developing depr

Updated on: February 03,2024

Higher cortisol levels may help predict risk of people developing depression in the future

by Trinity College DublinBall-and-stick model of the cortisol (hydrocortisone) molecule. Credit: Public DomainHigher levels of the stress hormone cortisol may increase the risk of developing depr

Updated on:February 03,2024

Men with sex addiction may have elevated levels of the 'love hormone'

by The Endocrine SocietyCredit: CC0 Public DomainMen with hypersexual disorder may have higher levels of oxytocin in their blood than men without the disorder, according to a small study publishe

Updated on: February 05,2024

Men with sex addiction may have elevated levels of the 'love hormone'

by The Endocrine SocietyCredit: CC0 Public DomainMen with hypersexual disorder may have higher levels of oxytocin in their blood than men without the disorder, according to a small study publishe

Updated on:February 05,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on: January 31,2024

Higher blood fats more harmful than first thought

by University of LeedsMicroscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee RobertsIncreased levels of blood

Updated on:January 31,2024

Study shows medial preoptic area mediates depressive-like behaviors associated with ovarian hormone fluctuations

by Ingrid Fadelli , Medical XpressElectrophysiological recording from MPOA GABAergic neurons (Vgat+) demonstrated that these neurons reduced their spiking activity in HW-treated mice compared to non-H

Updated on: January 22,2024

Study shows medial preoptic area mediates depressive-like behaviors associated with ovarian hormone fluctuations

by Ingrid Fadelli , Medical XpressElectrophysiological recording from MPOA GABAergic neurons (Vgat+) demonstrated that these neurons reduced their spiking activity in HW-treated mice compared to non-H

Updated on:January 22,2024

New findings on how to avert excessive weight loss from COVID-19

by Karolinska InstitutetSchematic illustration of mechanisms underlying SARS-CoV-2-induced adipose atrophy and weight loss. SARS-CoV-2 infection triggers dyspnea and pathological changes in the i

Updated on: January 31,2024

New findings on how to avert excessive weight loss from COVID-19

by Karolinska InstitutetSchematic illustration of mechanisms underlying SARS-CoV-2-induced adipose atrophy and weight loss. SARS-CoV-2 infection triggers dyspnea and pathological changes in the i

Updated on:January 31,2024