TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on: May 19,2026

TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on:May 19,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on: May 19,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on:May 19,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on: May 15,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on:May 15,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on: April 27,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on:April 27,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on: April 22,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on:April 22,2026

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of

Updated on: April 16,2026

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of

Updated on:April 16,2026

3 million-cell map shows menopause reshapes breast tissue, possibly raising cancer risk

byUniversity of CambridgeCredit: RDNE Stock project from PexelsScientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age—

Updated on: April 11,2026

3 million-cell map shows menopause reshapes breast tissue, possibly raising cancer risk

byUniversity of CambridgeCredit: RDNE Stock project from PexelsScientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age—

Updated on:April 11,2026

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Updated on: April 09,2026

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Updated on:April 09,2026

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based

Updated on: April 07,2026

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based

Updated on:April 07,2026

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a

Updated on: April 07,2026

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a

Updated on:April 07,2026

Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery

byUniversity of Colorado at BoulderA microscopic image of the researchers' sound-responsive particles. Credit: Andrew Goodwin/University of Colorado BoulderCancer is one of the leading causes of d

Updated on: April 06,2026

Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery

byUniversity of Colorado at BoulderA microscopic image of the researchers' sound-responsive particles. Credit: Andrew Goodwin/University of Colorado BoulderCancer is one of the leading causes of d

Updated on:April 06,2026

Transforming cancer treatment with ultrasound

by Dan Bernardi,Syracuse UniversityCredit:Chemical Science(2025). DOI: 10.1039/d5sc05710hChemotherapy has long been a cornerstone of cancer treatment, but its effectiveness comes at a cost. The powerf

Updated on: April 05,2026

Transforming cancer treatment with ultrasound

by Dan Bernardi,Syracuse UniversityCredit:Chemical Science(2025). DOI: 10.1039/d5sc05710hChemotherapy has long been a cornerstone of cancer treatment, but its effectiveness comes at a cost. The powerf

Updated on:April 05,2026