A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

Updated on: December 21,2024

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

Updated on:December 21,2024

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live

Updated on: December 21,2024

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live

Updated on:December 21,2024

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

Updated on: December 21,2024

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

Updated on:December 21,2024

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Updated on: December 21,2024

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Updated on:December 21,2024

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202

Updated on: December 21,2024

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202

Updated on:December 21,2024

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

Updated on: December 21,2024

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

Updated on:December 21,2024

Colorectal cancer risk factors important to consider for rescreening interval

by Lori SolomonColorectal cancer (CRC) risk factors are important to consider when making decisions for colonoscopy rescreening following negative colonoscopy screening (NCS) results (no presence of C

Updated on: December 21,2024

Colorectal cancer risk factors important to consider for rescreening interval

by Lori SolomonColorectal cancer (CRC) risk factors are important to consider when making decisions for colonoscopy rescreening following negative colonoscopy screening (NCS) results (no presence of C

Updated on:December 21,2024

Study identifies 'turncoat' cells that fight—and aid—cancer

by Michael Masciadrelli,Yale UniversityCirculating tumor antigen reactive T cells in patients with advanced melanoma. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-02023-4Y

Updated on: December 21,2024

Study identifies 'turncoat' cells that fight—and aid—cancer

by Michael Masciadrelli,Yale UniversityCirculating tumor antigen reactive T cells in patients with advanced melanoma. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-02023-4Y

Updated on:December 21,2024

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s

Updated on: December 20,2024

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s

Updated on:December 20,2024

Patients with MAFLD have 4.7 times higher risk of developing liver cancer, study finds

by Korea University College of MedicineEvolutionary changes in MASLD are associated with differential risks of hepatocellular carcinoma. Credit: Korea University MedicineResearch has revealed that in

Updated on: December 20,2024

Patients with MAFLD have 4.7 times higher risk of developing liver cancer, study finds

by Korea University College of MedicineEvolutionary changes in MASLD are associated with differential risks of hepatocellular carcinoma. Credit: Korea University MedicineResearch has revealed that in

Updated on:December 20,2024

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT:

Updated on: December 20,2024

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT:

Updated on:December 20,2024

Prevention and screening outpace treatment advances for averting death from five cancer types, study reveals

byNational Cancer InstituteCredit: Pixabay/CC0 Public DomainImprovements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than t

Updated on: December 20,2024

Prevention and screening outpace treatment advances for averting death from five cancer types, study reveals

byNational Cancer InstituteCredit: Pixabay/CC0 Public DomainImprovements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than t

Updated on:December 20,2024