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Hematology&Oncology
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Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from
Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a
WISDOM trial weighs risk-based cancer screening

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based
Transforming cancer treatment with ultrasound

Transforming cancer treatment with ultrasound

by Dan Bernardi,Syracuse UniversityCredit:Chemical Science(2025). DOI: 10.1039/d5sc05710hChemotherapy has long been a cornerstone of cancer treatment, but its effectiveness comes at a cost. The powerf

Transforming cancer treatment with ultrasound

by Dan Bernardi,Syracuse UniversityCredit:Chemical Science(2025). DOI: 10.1039/d5sc05710hChemotherapy has long been a cornerstone of cancer treatment, but its effectiveness comes at a cost. The powerf
Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery

Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery

byUniversity of Colorado at BoulderA microscopic image of the researchers' sound-responsive particles. Credit: Andrew Goodwin/University of Colorado BoulderCancer is one of the leading causes of d

Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery

byUniversity of Colorado at BoulderA microscopic image of the researchers' sound-responsive particles. Credit: Andrew Goodwin/University of Colorado BoulderCancer is one of the leading causes of d
Supportive cancer care: Most patients say human touch outshines tech

Supportive cancer care: Most patients say human touch outshines tech

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew researchpublishedin the November 2025 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkexplores the percep

Supportive cancer care: Most patients say human touch outshines tech

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew researchpublishedin the November 2025 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkexplores the percep
T cell therapies show long-term HPV gains

T cell therapies show long-term HPV gains

by Krista Didzbalis,Rutgers UniversityCredit: Pixabay/CC0 Public DomainResearchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI)—designated Comprehensive Cancer

T cell therapies show long-term HPV gains

by Krista Didzbalis,Rutgers UniversityCredit: Pixabay/CC0 Public DomainResearchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI)—designated Comprehensive Cancer
Targeting B-cells may boost immunotherapy in liver cancer treatment

Targeting B-cells may boost immunotherapy in liver cancer treatment

byHouston MethodistICB immunotherapy increased B-cell infiltration. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-66581-3Scientists have identified a promising strategy to improve liver

Targeting B-cells may boost immunotherapy in liver cancer treatment

byHouston MethodistICB immunotherapy increased B-cell infiltration. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-66581-3Scientists have identified a promising strategy to improve liver
Subtyping colorectal cancer may improve patient outcome predictions

Subtyping colorectal cancer may improve patient outcome predictions

byKyoto UniversityAn example usage of General Colorectal Cancer Signature (GCS). Credit: KyotoU / Makoto TaketoColorectal cancer, or CRC, is the world's second most lethal cancer based on the numb

Subtyping colorectal cancer may improve patient outcome predictions

byKyoto UniversityAn example usage of General Colorectal Cancer Signature (GCS). Credit: KyotoU / Makoto TaketoColorectal cancer, or CRC, is the world's second most lethal cancer based on the numb
Ultrasensitive liquid biopsy affective in predicting and monitoring immunotherapy response, study shows

Ultrasensitive liquid biopsy affective in predicting and monitoring immunotherapy response, study shows

byVall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPublishedtoday inClinical Cancer Research, findings from a study led by investigators at the Vall d'Hebron Institute of O

Ultrasensitive liquid biopsy affective in predicting and monitoring immunotherapy response, study shows

byVall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPublishedtoday inClinical Cancer Research, findings from a study led by investigators at the Vall d'Hebron Institute of O
Rearranging tumor cell structures—new approach could treat cancer

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan
Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M