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Hematology&Oncology
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Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

byCity of Hope National Medical CenterStructure showing the targetable sites of the City of Hope-discovered YTHDF2 protein. Credit: Dr. Jianjun Chen's Lab / City of HopeScientists at City of

Scientists uncover protein that helps cancer cells dodge CAR T cell therapy

byCity of Hope National Medical CenterStructure showing the targetable sites of the City of Hope-discovered YTHDF2 protein. Credit: Dr. Jianjun Chen's Lab / City of HopeScientists at City of
CRISPR study silences gene mutations that drive aggressive cancers

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc
Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat
Cell-based immunotherapy shows promise in early clinical trial for breast cancer

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar
Breast cancer risk increases with weight gain after age 35, finds study

Breast cancer risk increases with weight gain after age 35, finds study

by Elana GotkineThe risk for breast cancer is increased with weight gain after age 35 years, according to a research letter recentlypublishedinCancer Biology & Medicine.Katherine

Breast cancer risk increases with weight gain after age 35, finds study

by Elana GotkineThe risk for breast cancer is increased with weight gain after age 35 years, according to a research letter recentlypublishedinCancer Biology & Medicine.Katherine
Abnormal prenatal blood test results could indicate hidden maternal cancers

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet
Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability
A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human
Changes in blood cell production over the lifetime could impact leukemia outcomes

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
First look at neuron–tumor connections in brain illuminates formation and spread of gliomas

First look at neuron–tumor connections in brain illuminates formation and spread of gliomas

by Stephanie Dutchen,Harvard Medical SchoolResearchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green. Image: Annie Hsieh. Credit:Proceedi

First look at neuron–tumor connections in brain illuminates formation and spread of gliomas

by Stephanie Dutchen,Harvard Medical SchoolResearchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green. Image: Annie Hsieh. Credit:Proceedi