Advancing noninvasive diagnosis of NASH: Potential of sequential ultrasound molecular imaging in NAFLD/MAFLD

by KeAi Communications Co.Animal study flowchart and schematic illustration of sequential USMI. Credit:Liver Research(2023). DOI: 10.1016/j.livres.2023.11.002Non-alcoholic fatty liver dise

Updated on: March 07,2024 10

Advancing noninvasive diagnosis of NASH: Potential of sequential ultrasound molecular imaging in NAFLD/MAFLD

by KeAi Communications Co.Animal study flowchart and schematic illustration of sequential USMI. Credit:Liver Research(2023). DOI: 10.1016/j.livres.2023.11.002Non-alcoholic fatty liver dise

Updated on:March 07,2024 10

Multiple myeloma cured after hepatitis treatment reveals that this cancer can be caused by viruses

JANUARY 19, 2024byThe Spanish National Cancer Research CentreThe effect of antiviral treatment in hepatitis C virus- and hepatitis B virus-infected multiple myeloma cohorts. (A) Study design and

Updated on: March 15,2024 7

Multiple myeloma cured after hepatitis treatment reveals that this cancer can be caused by viruses

JANUARY 19, 2024byThe Spanish National Cancer Research CentreThe effect of antiviral treatment in hepatitis C virus- and hepatitis B virus-infected multiple myeloma cohorts. (A) Study design and

Updated on:March 15,2024 7

Overcoming barriers to conducting clinical trials in childhood rare disease research

FEBRUARY 29, 2024byThe Hospital for Sick ChildrenGraphical abstract. Credit:Hepatology(2023). DOI: 10.1097/HEP.0000000000000727Using a novel methodology, researchers at The Hospital

Updated on: March 15,2024 5

Overcoming barriers to conducting clinical trials in childhood rare disease research

FEBRUARY 29, 2024byThe Hospital for Sick ChildrenGraphical abstract. Credit:Hepatology(2023). DOI: 10.1097/HEP.0000000000000727Using a novel methodology, researchers at The Hospital

Updated on:March 15,2024 5

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on: March 20,2024 10

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on:March 20,2024 10

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on: March 20,2024 18

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on:March 20,2024 18

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on: March 20,2024 13

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on:March 20,2024 13

Exploring how the liver immune system eats up 'bad cholesterol'

by Karolinska InstitutetCredit: CC0 Public DomainA new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholest

Updated on: March 20,2024 14

Exploring how the liver immune system eats up 'bad cholesterol'

by Karolinska InstitutetCredit: CC0 Public DomainA new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholest

Updated on:March 20,2024 14

Impact of onset time, number, type, and sequence of extrahepatic organ failure on prognosis of liver failure

by Xia & He Publishing Inc.Graphical abstract. Credit:Journal of Clinical and Translational Hepatology(2024). DOI: 10.14218/JCTH.2023.00379The impact of the characteristics of extrahep

Updated on: March 20,2024 20

Impact of onset time, number, type, and sequence of extrahepatic organ failure on prognosis of liver failure

by Xia & He Publishing Inc.Graphical abstract. Credit:Journal of Clinical and Translational Hepatology(2024). DOI: 10.14218/JCTH.2023.00379The impact of the characteristics of extrahep

Updated on:March 20,2024 20

Understanding chronic liver disease through mitochondria

by First Hospital of Jilin University(1) Degradation of mitochondria matrix, inner membrane and intermembrane oxidized or misfolded protein by mitochondrial proteases. (2) Ubiquitinated outer mitochon

Updated on: March 20,2024 11

Understanding chronic liver disease through mitochondria

by First Hospital of Jilin University(1) Degradation of mitochondria matrix, inner membrane and intermembrane oxidized or misfolded protein by mitochondrial proteases. (2) Ubiquitinated outer mitochon

Updated on:March 20,2024 11

Exposure to toxic blue-green algae, exacerbated by climate change, shown to cause liver disease in mouse models

by University of California, IrvineCYN exposure in mice for 15 days via oral gavage caused an altered gut bacteriome pattern at both phylum and family levels with decreased α-diversity. (A) The r

Updated on: March 25,2024 11

Exposure to toxic blue-green algae, exacerbated by climate change, shown to cause liver disease in mouse models

by University of California, IrvineCYN exposure in mice for 15 days via oral gavage caused an altered gut bacteriome pattern at both phylum and family levels with decreased α-diversity. (A) The r

Updated on:March 25,2024 11

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on: March 25,2024 10

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on:March 25,2024 10

Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth

byThe Spanish National Cancer Research CentreOral feeding activates a 'GPS gen' in liver cells. Credit: underbau / CNIOIn mammals, the liver detects the body's energy demand at any g

Updated on: March 27,2024 0

Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth

byThe Spanish National Cancer Research CentreOral feeding activates a 'GPS gen' in liver cells. Credit: underbau / CNIOIn mammals, the liver detects the body's energy demand at any g

Updated on:March 27,2024 0