First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on: April 20,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on:April 20,2024

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on: April 24,2024

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on:April 24,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on: March 27,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on:March 27,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on: May 06,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on:May 06,2024

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on: July 23,2024

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on:July 23,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on: May 08,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on:May 08,2024

Decline in risk of dementia and heart failure in patients with rheumatoid arthritis

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainRheumatoid arthritis (RA) is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It

Updated on: May 08,2024

Decline in risk of dementia and heart failure in patients with rheumatoid arthritis

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainRheumatoid arthritis (RA) is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It

Updated on:May 08,2024

'New era and treatment of breast cancer': AI is helping detect breast cancer earlier

by Michelle Marchante, Miami HeraldThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on: March 13,2024

'New era and treatment of breast cancer': AI is helping detect breast cancer earlier

by Michelle Marchante, Miami HeraldThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on:March 13,2024

Experimental bone can help osteoarthritis patients

by Kaunas University of TechnologyCredit: CC0 Public DomainResearchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone

Updated on: April 17,2024

Experimental bone can help osteoarthritis patients

by Kaunas University of TechnologyCredit: CC0 Public DomainResearchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone

Updated on:April 17,2024