A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024 13

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024 13

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on: April 28,2024 0

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on:April 28,2024 0

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on: April 20,2024 18

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on:April 20,2024 18

Do bacteria in the mouth affect risk of developing rheumatoid arthritis?

by WileyCredit: CC0 Public DomainInvestigators found similarities in the bacterial composition of the mouth among patients with early rheumatoid arthritis and those at risk of developing the dise

Updated on: May 26,2024 4

Do bacteria in the mouth affect risk of developing rheumatoid arthritis?

by WileyCredit: CC0 Public DomainInvestigators found similarities in the bacterial composition of the mouth among patients with early rheumatoid arthritis and those at risk of developing the dise

Updated on:May 26,2024 4

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024 20

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024 20

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024 19

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024 19

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024 16

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024 16

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on: June 06,2024 3

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on:June 06,2024 3

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024 18

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024 18

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024 10

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024 10

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on: April 08,2024 14

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on:April 08,2024 14

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on: April 24,2024 19

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on:April 24,2024 19