Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on: July 09,2024 0

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on:July 09,2024 0

Short sleep duration causally linked to rheumatoid arthritis

Short sleep duration is causally associated with an increased risk for rheumatoid arthritis (RA), according to a study published online June 30 inFrontiers in Public Health.Rui-Chen Gao, from th

Updated on: June 06,2024 6

Short sleep duration causally linked to rheumatoid arthritis

Short sleep duration is causally associated with an increased risk for rheumatoid arthritis (RA), according to a study published online June 30 inFrontiers in Public Health.Rui-Chen Gao, from th

Updated on:June 06,2024 6

Researchers uncover new cell types involved in osteoarthritis

by Valerie Goodwin,University of MichiganCredit: Unsplash/CC0 Public DomainA Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint diseas

Updated on: June 28,2024 3

Researchers uncover new cell types involved in osteoarthritis

by Valerie Goodwin,University of MichiganCredit: Unsplash/CC0 Public DomainA Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint diseas

Updated on:June 28,2024 3

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on: June 17,2024 5

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on:June 17,2024 5

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024 8

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024 8

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024 7

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024 7

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on: June 17,2024 3

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on:June 17,2024 3

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on: June 17,2024 7

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on:June 17,2024 7

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on: September 02,2024 0

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on:September 02,2024 0

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024 0

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024 0

One in five patients with rheumatoid arthritis went undiagnosed during the pandemic

by King's College LondonCredit: Unsplash/CC0 Public DomainThe number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.The

Updated on: May 29,2024 5

One in five patients with rheumatoid arthritis went undiagnosed during the pandemic

by King's College LondonCredit: Unsplash/CC0 Public DomainThe number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.The

Updated on:May 29,2024 5