How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on: June 15,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on:June 15,2024

COVID: On the lookout for new antibodies

by Friedrich–Alexander University Erlangen–NurnbergCredit: Pixabay/CC0 Public DomainA team of researchers at FAU and Universitätsklinikum Erlangen has gained new insights into the maturation of S

Updated on: April 13,2024

COVID: On the lookout for new antibodies

by Friedrich–Alexander University Erlangen–NurnbergCredit: Pixabay/CC0 Public DomainA team of researchers at FAU and Universitätsklinikum Erlangen has gained new insights into the maturation of S

Updated on:April 13,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on: March 24,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on:March 24,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Updated on: March 24,2024

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Updated on:March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on: May 08,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on:May 08,2024