ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024

Gut bacteria can process dietary fiber into an anti-allergy weapon, finds new study

by Tokyo University of ScienceGut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail th

Updated on: March 07,2024

Gut bacteria can process dietary fiber into an anti-allergy weapon, finds new study

by Tokyo University of ScienceGut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail th

Updated on:March 07,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on: April 22,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on:April 22,2024

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on: April 22,2024

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on:April 22,2024

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on: April 06,2024

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on:April 06,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024

C-reactive protein reduces the immune response in inflammatory disease

by Karin Söderlund Leifler,Linköping UniversityGraphical abstract. Credit:Journal of Autoimmunity(2023). DOI: 10.1016/j.jaut.2023.102998The biological function of the C-reactive prot

Updated on: April 13,2024

C-reactive protein reduces the immune response in inflammatory disease

by Karin Söderlund Leifler,Linköping UniversityGraphical abstract. Credit:Journal of Autoimmunity(2023). DOI: 10.1016/j.jaut.2023.102998The biological function of the C-reactive prot

Updated on:April 13,2024

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on: March 24,2024

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on:March 24,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on: January 26,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on:January 26,2024

Race, ethnic disparities seen in age-adjusted prevalence of arthritis

by Elana GotkineThe age-adjusted prevalence of arthritis varies by race and ethnicity, with higher prevalence seen among American Indian/Alaska Native adults, according to a studypublished

Updated on: July 23,2024

Race, ethnic disparities seen in age-adjusted prevalence of arthritis

by Elana GotkineThe age-adjusted prevalence of arthritis varies by race and ethnicity, with higher prevalence seen among American Indian/Alaska Native adults, according to a studypublished

Updated on:July 23,2024

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

by Maria Fernanda Ziegler,FAPESPThe systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit:npj Aging(2023). DOI: 10.1038/s41514-02

Updated on: April 10,2024

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

by Maria Fernanda Ziegler,FAPESPThe systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit:npj Aging(2023). DOI: 10.1038/s41514-02

Updated on:April 10,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024