An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on: November 01,2024

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on:November 01,2024

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on: April 28,2024

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on:April 28,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on: April 10,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on:April 10,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on: March 24,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on:March 24,2024

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on: March 13,2024

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on:March 13,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on: May 08,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on:May 08,2024

Prototype equipment can detect rheumatoid arthritis

by University of TwenteCredit: University of TwenteAccording to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners h

Updated on: March 30,2024

Prototype equipment can detect rheumatoid arthritis

by University of TwenteCredit: University of TwenteAccording to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners h

Updated on:March 30,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on: April 08,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on:April 08,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on: March 05,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on:March 05,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024