Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on: June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on:June 01,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on: March 25,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on:March 25,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on: June 15,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on:June 15,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on: April 08,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on:April 08,2024

What you need to know about new treatments for children with peanut allergies

by Dr Li Huang, et al.,University of MelbourneCredit: Unsplash/CC0 Public DomainFor many people peanuts are a healthy snacking option, but for those people with an allergy, peanuts can be a seri

Updated on: March 27,2024

What you need to know about new treatments for children with peanut allergies

by Dr Li Huang, et al.,University of MelbourneCredit: Unsplash/CC0 Public DomainFor many people peanuts are a healthy snacking option, but for those people with an allergy, peanuts can be a seri

Updated on:March 27,2024

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on: May 07,2024

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on:May 07,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024