Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024 0

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024 0

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on: April 20,2024 18

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on:April 20,2024 18

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024 11

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024 11

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024 14

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024 14

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024 11

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024 11

Does COVID really damage your immune system and make you more vulnerable to infections? The evidence is lacking

by Sheena Cruickshank,The ConversationCredit: AI-generated imageOver the past month or two, manynorthern hemisphere countriesincluding the U.S. and the U.K. have seen a large wave of

Updated on: April 13,2024 20

Does COVID really damage your immune system and make you more vulnerable to infections? The evidence is lacking

by Sheena Cruickshank,The ConversationCredit: AI-generated imageOver the past month or two, manynorthern hemisphere countriesincluding the U.S. and the U.K. have seen a large wave of

Updated on:April 13,2024 20

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on: May 05,2024 13

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on:May 05,2024 13

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024 5

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024 5

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on: March 24,2024 20

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on:March 24,2024 20

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on: March 27,2024 0

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on:March 27,2024 0

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on: April 17,2024 17

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on:April 17,2024 17

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024 8

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024 8