The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024 12

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024 12

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024 16

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024 16

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024 13

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024 13

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on: April 08,2024 15

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on:April 08,2024 15

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on: May 06,2024 13

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on:May 06,2024 13

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on: March 25,2024 14

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on:March 25,2024 14

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on: November 21,2024 0

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on:November 21,2024 0

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024 16

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024 16

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on: April 08,2024 14

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on:April 08,2024 14

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on: April 15,2024 20

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on:April 15,2024 20

Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on: April 10,2024 16

Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on:April 10,2024 16

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024 18

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024 18