Proinflammatory diet tied to higher risk for chronic kidney disease

Updated on 2025-05-26 00:00:00 0 0

by Lori Solomon

Individuals who eat a proinflammatory diet have a higher likelihood of chronic kidney disease, according to a review published online April 16 in the Journal of Health, Population and Nutrition.

Amirhossein Ataei Kachouei, from Isfahan University of Medical Sciences in Iran, and colleagues conducted a systematic literature review to examine the association between the dietary inflammatory index and chronic kidney disease and estimated glomerular filtration rate. The random-effects model was used for statistical analysis, and pooled effect sizes were reported as odds ratios.

Based on 13 cross-sectional studies, the researchers found that higher dietary inflammatory index scores were associated with significantly higher odds of chronic kidney disease (odds ratio, 1.36) and a low estimated glomerular filtration rate (odds ratio, 1.58).

"This study found a significant positive association between the dietary inflammatory index and the odds of chronic kidney disease and low-estimated glomerular filtration rate, suggesting a higher likelihood of chronic kidney disease in individuals who adhere to a proinflammatory diet, " the authors write.

"Large-scale prospective cohort studies are required to confirm these findings, particularly by assessing different indicators of kidney function."

More information: Amirhossein Ataei Kachouei et al, Association between dietary inflammatory index and risk of chronic kidney disease and low glomerular filtration rate; a systematic review and meta-analysis of observational studies, Journal of Health, Population and Nutrition (2025). DOI: 10.1186/s41043-025-00872-9

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