Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on: February 27,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on:February 27,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024

Innovative 'smart socks' could help millions living with dementia

by University of BristolLeft: The display that carers will see in the Milbotix app. Right: Milbotix founder and CEO Dr Zeke Steer. Credit: University of Bristol"Smart socks" that track

Updated on: May 13,2024

Innovative 'smart socks' could help millions living with dementia

by University of BristolLeft: The display that carers will see in the Milbotix app. Right: Milbotix founder and CEO Dr Zeke Steer. Credit: University of Bristol"Smart socks" that track

Updated on:May 13,2024

Brain's 'wakeful rest' network may be key to Alzheimer's risk

by Amanda Steffen,Yale UniversityCredit: Unsplash/CC0 Public DomainIf you have ever let your mind wander, you have relied on the brain's default mode network (DMN). Scientifically, the DMN i

Updated on: February 21,2024

Brain's 'wakeful rest' network may be key to Alzheimer's risk

by Amanda Steffen,Yale UniversityCredit: Unsplash/CC0 Public DomainIf you have ever let your mind wander, you have relied on the brain's default mode network (DMN). Scientifically, the DMN i

Updated on:February 21,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on: March 05,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on:March 05,2024

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on: March 02,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on:March 02,2024

'Super-agers' study may reveal secrets to staying young

Mary Helen Abbott, 77, paints her lips bright pink, still smokes the occasional cigarette, keeps up on all the gossip at the retirement home and wears a short skirt to fitness class.She giggles as the

Updated on: February 26,2024

'Super-agers' study may reveal secrets to staying young

Mary Helen Abbott, 77, paints her lips bright pink, still smokes the occasional cigarette, keeps up on all the gossip at the retirement home and wears a short skirt to fitness class.She giggles as the

Updated on:February 26,2024

Tardive dyskinesia impacts patients and caregivers

by Lori SolomonTardive dyskinesia (TD) poses a substantial burden for both caregivers and patients, according to a study published online Nov. 28 in theJournal of Patient-Reported Outcomes.Rakes

Updated on: February 03,2024

Tardive dyskinesia impacts patients and caregivers

by Lori SolomonTardive dyskinesia (TD) poses a substantial burden for both caregivers and patients, according to a study published online Nov. 28 in theJournal of Patient-Reported Outcomes.Rakes

Updated on:February 03,2024