New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on: April 20,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on:April 20,2024

Disruption of brain-blood barrier might influence progression of Alzheimer's

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.More and more data from preclinical and clinical st

Updated on: February 26,2024

Disruption of brain-blood barrier might influence progression of Alzheimer's

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.More and more data from preclinical and clinical st

Updated on:February 26,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Using light to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Deposits of Beta-Amyloid in Fruit Flies Stopped by Using Porphyrin and Blue LED Lights. Credit: KAISTA Korean research team jointl

Updated on: February 27,2024

Using light to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Deposits of Beta-Amyloid in Fruit Flies Stopped by Using Porphyrin and Blue LED Lights. Credit: KAISTA Korean research team jointl

Updated on:February 27,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on: January 12,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on:January 12,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024

Record month for dementia diagnosis shows need for better tools, treatments

by Alzheimer's Research UKCredit: CC0 Public DomainAlzheimer's Research UK is calling for continued improvements in the way the UK diagnoses and treats dementia after a record number of p

Updated on: May 11,2024

Record month for dementia diagnosis shows need for better tools, treatments

by Alzheimer's Research UKCredit: CC0 Public DomainAlzheimer's Research UK is calling for continued improvements in the way the UK diagnoses and treats dementia after a record number of p

Updated on:May 11,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on: May 11,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on:May 11,2024

Traditional foods can bring joy to dementia patients

(HealthDay)—For patients with dementia, traditional dishes can create joy and boost patients' sense of well-being, according to research published online Jan. 11 in theJournal of Clinical Nu

Updated on: February 27,2024

Traditional foods can bring joy to dementia patients

(HealthDay)—For patients with dementia, traditional dishes can create joy and boost patients' sense of well-being, according to research published online Jan. 11 in theJournal of Clinical Nu

Updated on:February 27,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on: February 05,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on:February 05,2024