AI stroke brain scan readings found to be twice as accurate as current method

by Samantha Rey,Imperial College LondonMethods overview. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01325-zNew AI software can read the brain scans of patients who ha

Updated on: December 17,2024

AI stroke brain scan readings found to be twice as accurate as current method

by Samantha Rey,Imperial College LondonMethods overview. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01325-zNew AI software can read the brain scans of patients who ha

Updated on:December 17,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on: March 07,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on:March 07,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on: March 02,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on:March 02,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on: March 28,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on:March 28,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on: March 09,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on:March 09,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on: February 26,2024

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on:February 26,2024