A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on: March 28,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on:March 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on: February 21,2024

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on:February 21,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on: April 02,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on:April 02,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on: April 06,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on:April 06,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024