Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on: March 28,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on:March 28,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on: November 28,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on:November 28,2024

Epigenetic markers associated with Alzheimer's disease found

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers from the Brigham and Women's Hospital, Harvard Medical School and the Dana-Farber Cancer Institute in the U.S., and Shan

Updated on: June 01,2024

Epigenetic markers associated with Alzheimer's disease found

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers from the Brigham and Women's Hospital, Harvard Medical School and the Dana-Farber Cancer Institute in the U.S., and Shan

Updated on:June 01,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on: January 11,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on:January 11,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on: March 05,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on:March 05,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on: April 08,2024

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on:April 08,2024