New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024 7

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024 7

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024 17

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024 17

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024 16

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024 16

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on: February 24,2024 17

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on:February 24,2024 17

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024 8

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024 8

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on: February 21,2024 20

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on:February 21,2024 20

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on: April 08,2024 12

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on:April 08,2024 12

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024 0

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024 0

Bill Gates giving $50 million for Alzheimer's research

Microsoft co-founder Bill Gates announced Monday that he is investing $50 million to fund research into treatment for Alzheimer's disease.Gates, in an entry on his blog, said he was making the inv

Updated on: March 07,2024 19

Bill Gates giving $50 million for Alzheimer's research

Microsoft co-founder Bill Gates announced Monday that he is investing $50 million to fund research into treatment for Alzheimer's disease.Gates, in an entry on his blog, said he was making the inv

Updated on:March 07,2024 19

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024 17

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024 17

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on: March 07,2024 13

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on:March 07,2024 13

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on: June 24,2024 4

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on:June 24,2024 4