The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024 10

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024 10

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on: June 04,2024 4

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on:June 04,2024 4

Research on advanced Alzheimer's disease investigates novel ways to restore cognitive function

by Ellen Goldbaum,University at BuffaloCredit: Wikimedia CommonsWhile most research on Alzheimer's disease (AD) has focused on early diagnosis and treatment, University at Buffalo scientists

Updated on: May 26,2024 8

Research on advanced Alzheimer's disease investigates novel ways to restore cognitive function

by Ellen Goldbaum,University at BuffaloCredit: Wikimedia CommonsWhile most research on Alzheimer's disease (AD) has focused on early diagnosis and treatment, University at Buffalo scientists

Updated on:May 26,2024 8

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024 14

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024 14

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on: April 02,2024 15

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on:April 02,2024 15

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024 13

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024 13

Devastating causes of childhood dementia revealed

by Jessica Stanley,University of AdelaideOverall survival of the cohort born with currently untreatable childhood dementia. Credit:Brain(2023). DOI: 10.1093/brain/awad242It is a hear

Updated on: March 02,2024 17

Devastating causes of childhood dementia revealed

by Jessica Stanley,University of AdelaideOverall survival of the cohort born with currently untreatable childhood dementia. Credit:Brain(2023). DOI: 10.1093/brain/awad242It is a hear

Updated on:March 02,2024 17

Multi-gene test predicts Alzheimer's better than APOE E4 alone

by Laura Kurtzman,University of California, San FranciscoPET scan of a human brain with Alzheimer's disease. Credit: public domainA new test that combines the effects of more than two dozen

Updated on: May 28,2024 8

Multi-gene test predicts Alzheimer's better than APOE E4 alone

by Laura Kurtzman,University of California, San FranciscoPET scan of a human brain with Alzheimer's disease. Credit: public domainA new test that combines the effects of more than two dozen

Updated on:May 28,2024 8

Repetitive negative thinking linked to dementia risk

by University College LondonCredit: Pixabay/CC0 Public DomainPersistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study.In the st

Updated on: June 01,2024 6

Repetitive negative thinking linked to dementia risk

by University College LondonCredit: Pixabay/CC0 Public DomainPersistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study.In the st

Updated on:June 01,2024 6

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on: January 11,2024 20

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on:January 11,2024 20

Discovery of a disease-specific biomarker for amyotrophic lateral sclerosis

byUniversity of TsukubaCredit: AI-generated imageSporadic amyotrophic lateral sclerosis (ALS) accounts for 90% of all ALS cases. Researchers from the University of Tsukuba discovered that the ed

Updated on: April 09,2024 0

Discovery of a disease-specific biomarker for amyotrophic lateral sclerosis

byUniversity of TsukubaCredit: AI-generated imageSporadic amyotrophic lateral sclerosis (ALS) accounts for 90% of all ALS cases. Researchers from the University of Tsukuba discovered that the ed

Updated on:April 09,2024 0

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on: June 26,2024 7

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on:June 26,2024 7