Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on: November 12,2024 0

Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on:November 12,2024 0

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on: April 09,2024 0

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on:April 09,2024 0

Study shows that attractor dynamics in the monkey prefrontal cortex reflect the confidence of decisions

by Ingrid Fadelli , Medical XpressTemporal-discounting task performed by monkeys during the team's experiments. In each trial, the animals first touched a bar, after which a red dot was presented.

Updated on: January 11,2024 18

Study shows that attractor dynamics in the monkey prefrontal cortex reflect the confidence of decisions

by Ingrid Fadelli , Medical XpressTemporal-discounting task performed by monkeys during the team's experiments. In each trial, the animals first touched a bar, after which a red dot was presented.

Updated on:January 11,2024 18

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on: January 09,2024 5

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on:January 09,2024 5

Pregnancy and reproductive history may impact dementia risk

by Alzheimer's AssociationCredit: CC0 Public DomainResearch reported at the Alzheimer's Association International Conference (AAIC) 2018 in Chicago highlighted sex differences associated with

Updated on: June 07,2024 6

Pregnancy and reproductive history may impact dementia risk

by Alzheimer's AssociationCredit: CC0 Public DomainResearch reported at the Alzheimer's Association International Conference (AAIC) 2018 in Chicago highlighted sex differences associated with

Updated on:June 07,2024 6

New study reveals role of hippocampus in two functions of memory

by Krishna Ramanujan,Cornell UniversityAssociative and predictive codes in the hippocampus. Our optogenetic manipulation perturbed hippocampal sequences without affecting cell coactivity, thus s

Updated on: January 12,2024 19

New study reveals role of hippocampus in two functions of memory

by Krishna Ramanujan,Cornell UniversityAssociative and predictive codes in the hippocampus. Our optogenetic manipulation perturbed hippocampal sequences without affecting cell coactivity, thus s

Updated on:January 12,2024 19

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on: March 25,2024 6

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on:March 25,2024 6

A 'feeling' for dementia?

by German Center for Neurodegenerative DiseasesCredit: CC0 Public DomainA research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an

Updated on: May 26,2024 7

A 'feeling' for dementia?

by German Center for Neurodegenerative DiseasesCredit: CC0 Public DomainA research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an

Updated on:May 26,2024 7

New target for drug intervention in Alzheimer's disease identified

by University of Alabama at BirminghamInhibiting an enzyme called LIMK1 seems to improve the length and density of dendritic spines, shown here in green. Healthy dendritic spines are thought to h

Updated on: May 28,2024 8

New target for drug intervention in Alzheimer's disease identified

by University of Alabama at BirminghamInhibiting an enzyme called LIMK1 seems to improve the length and density of dendritic spines, shown here in green. Healthy dendritic spines are thought to h

Updated on:May 28,2024 8

High genetic risk of attention deficit hyperactivity disorder suggests possible health consequences

by Estonian Research CouncilCredit: Pixabay/CC0 Public DomainAttention deficit hyperactivity disorder (ADHD) is closely linked to a person's mental and physical health and is often accompanied by

Updated on: May 14,2024 0

High genetic risk of attention deficit hyperactivity disorder suggests possible health consequences

by Estonian Research CouncilCredit: Pixabay/CC0 Public DomainAttention deficit hyperactivity disorder (ADHD) is closely linked to a person's mental and physical health and is often accompanied by

Updated on:May 14,2024 0

Study unveils organizational complexity of the prefrontal cortex and neuron subtypes regulating chronic pain

by Ingrid Fadelli , Medical XpressOrganization of PFC neurons and transcriptional impact on each subtype under chronic pain state. A. Molecular and spatial identity of each neuronal subtype within PFC

Updated on: January 10,2024 11

Study unveils organizational complexity of the prefrontal cortex and neuron subtypes regulating chronic pain

by Ingrid Fadelli , Medical XpressOrganization of PFC neurons and transcriptional impact on each subtype under chronic pain state. A. Molecular and spatial identity of each neuronal subtype within PFC

Updated on:January 10,2024 11

Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on: March 19,2024 15

Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on:March 19,2024 15