Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases

bySanford-Burnham PrebysCredit: Pixabay/CC0 Public DomainDiseases marked by progressive deterioration of the brain—neurodegeneration—have proven challenging to understand and treat. These common

Updated on: January 08,2025

Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases

bySanford-Burnham PrebysCredit: Pixabay/CC0 Public DomainDiseases marked by progressive deterioration of the brain—neurodegeneration—have proven challenging to understand and treat. These common

Updated on:January 08,2025

A newly characterized form of tau may be involved in initiating Alzheimer's disease

JANUARY 22, 2024by Brandon Chase,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainThe tau protein accumulates in abnormal shapes in the brains of individuals with Alzheimer's d

Updated on: March 29,2024

A newly characterized form of tau may be involved in initiating Alzheimer's disease

JANUARY 22, 2024by Brandon Chase,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainThe tau protein accumulates in abnormal shapes in the brains of individuals with Alzheimer's d

Updated on:March 29,2024

Neuroscientists show movies 'play out' as an oscillatory symphony in the brain

Updated on: May 15,2025

Neuroscientists show movies 'play out' as an oscillatory symphony in the brain

Updated on:May 15,2025

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on: April 07,2024

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on:April 07,2024

Experts outline key research areas in neuropalliative care

Updated on: March 05,2025

Experts outline key research areas in neuropalliative care

Updated on:March 05,2025

Dementia treatments less likely to be prescribed in poorer areas of England

by Alzheimer's Research UKThe study, which also shows that these inequalities in England are not replicated in other parts of the UK, is published in the journalAge and Ageing.Four drug

Updated on: February 27,2024

Dementia treatments less likely to be prescribed in poorer areas of England

by Alzheimer's Research UKThe study, which also shows that these inequalities in England are not replicated in other parts of the UK, is published in the journalAge and Ageing.Four drug

Updated on:February 27,2024

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on: November 22,2024

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on:November 22,2024

Tracing brain circuits that tell us when to eat—and when to stop

Updated on: July 07,2025

Tracing brain circuits that tell us when to eat—and when to stop

Updated on:July 07,2025

Exploring the impact of meta learning on post-stroke motor recovery

byUniversity of TsukubaCredit: Unsplash/CC0 Public DomainThe variability in recovery performance among individuals who have suffered a stroke has puzzled clinicians. A research group from Univer

Updated on: August 08,2024

Exploring the impact of meta learning on post-stroke motor recovery

byUniversity of TsukubaCredit: Unsplash/CC0 Public DomainThe variability in recovery performance among individuals who have suffered a stroke has puzzled clinicians. A research group from Univer

Updated on:August 08,2024

New clues to Alzheimer's disease

by Alvin Powell,Harvard UniversityHarvard University McLean researchers Bruce Cohen, left, and Kai Sonntag have found an energy dysfunction in the cells of late-onset Alzheimer's patients, a

Updated on: April 07,2024

New clues to Alzheimer's disease

by Alvin Powell,Harvard UniversityHarvard University McLean researchers Bruce Cohen, left, and Kai Sonntag have found an energy dysfunction in the cells of late-onset Alzheimer's patients, a

Updated on:April 07,2024

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on: November 22,2024

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on:November 22,2024

Newborns experiencing neonatal seizures face an elevated risk of developing epilepsy, study shows

Updated on: March 25,2025

Newborns experiencing neonatal seizures face an elevated risk of developing epilepsy, study shows

Updated on:March 25,2025