Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on: March 07,2024 11

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on:March 07,2024 11

Lipid and glucose levels at age 35 associated with Alzheimer's disease

by Boston University School of MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainLiving your best life at 35, ignoring cholesterol and glucose levels, may impac

Updated on: March 13,2024 17

Lipid and glucose levels at age 35 associated with Alzheimer's disease

by Boston University School of MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainLiving your best life at 35, ignoring cholesterol and glucose levels, may impac

Updated on:March 13,2024 17

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024 0

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024 0

Strawberries may fend off Alzheimer's

byRush University Medical CenterCredit: CC0 Public DomainCould strawberries as a snack or in your cereal, salads or smoothie help protect your brain from Alzheimer's? Maybe so, according to

Updated on: April 18,2024 0

Strawberries may fend off Alzheimer's

byRush University Medical CenterCredit: CC0 Public DomainCould strawberries as a snack or in your cereal, salads or smoothie help protect your brain from Alzheimer's? Maybe so, according to

Updated on:April 18,2024 0

Snake venom may hold key to breaking down plaques that cause Alzheimer's disease

by Monash UniversityA toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms.

Updated on: February 28,2024 17

Snake venom may hold key to breaking down plaques that cause Alzheimer's disease

by Monash UniversityA toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms.

Updated on:February 28,2024 17

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024 4

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024 4

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024 13

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024 13

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024 0

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024 0

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20

Researchers discover possible new cause for Alzheimer's disease

by Arielle Robinson, The Atlanta Journal-ConstitutionCredit: Pixabay/Pete Linforth.Scientists at Oregon Health and Science University have made a development that could lead to a greater understanding

Updated on: March 02,2024 14

Researchers discover possible new cause for Alzheimer's disease

by Arielle Robinson, The Atlanta Journal-ConstitutionCredit: Pixabay/Pete Linforth.Scientists at Oregon Health and Science University have made a development that could lead to a greater understanding

Updated on:March 02,2024 14

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on: September 21,2024 0

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on:September 21,2024 0

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on: February 05,2024 17

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on:February 05,2024 17