A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on: May 23,2024 4

A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on:May 23,2024 4

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on: May 23,2024 7

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on:May 23,2024 7

Liquid biopsy chip detects tumor cells in 100 percent of blood samples from breast cancer patients

by Michael W. Dorsey,Worcester Polytechnic InstituteA circulating cancer cell (pink) attaches to carbon nanotube surface; white blood cells (blue) do not adhere and are later washed away. Credit

Updated on: May 23,2024 5

Liquid biopsy chip detects tumor cells in 100 percent of blood samples from breast cancer patients

by Michael W. Dorsey,Worcester Polytechnic InstituteA circulating cancer cell (pink) attaches to carbon nanotube surface; white blood cells (blue) do not adhere and are later washed away. Credit

Updated on:May 23,2024 5

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024 5

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024 5

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on: May 23,2024 3

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on:May 23,2024 3

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on: May 23,2024 6

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on:May 23,2024 6

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali

Updated on: May 23,2024 4

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali

Updated on:May 23,2024 4

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024 5

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024 5

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on: May 23,2024 7

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on:May 23,2024 7

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish

Updated on: May 23,2024 3

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish

Updated on:May 23,2024 3

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc

Updated on: May 23,2024 4

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc

Updated on:May 23,2024 4

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on: May 23,2024 7

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on:May 23,2024 7