Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Bacteria subtype linked to growth in up to 50% of human colorectal cancers, researchers report

byFred Hutchinson Cancer CenterA microscope image shows a human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color. The bacterium is commonly found in people'

Updated on: March 30,2024

Bacteria subtype linked to growth in up to 50% of human colorectal cancers, researchers report

byFred Hutchinson Cancer CenterA microscope image shows a human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color. The bacterium is commonly found in people'

Updated on:March 30,2024

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is

Updated on: January 23,2024

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is

Updated on:January 23,2024

What breast cancer risk assessments can tell you

by Justin Stebbing,The ConversationCredit: Unsplash/CC0 Public DomainActress Olivia Munn recently shared on social media that she had undergone a double mastectomy after being diagnosed with&nbs

Updated on: March 30,2024

What breast cancer risk assessments can tell you

by Justin Stebbing,The ConversationCredit: Unsplash/CC0 Public DomainActress Olivia Munn recently shared on social media that she had undergone a double mastectomy after being diagnosed with&nbs

Updated on:March 30,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on: February 03,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on:February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024

Screening age needs to be lowered to combat colorectal cancer 'epidemic,' say researchers

by University of OtagoCredit: Pixabay/CC0 Public DomainNew Zealand needs to lower the screening age for colorectal cancer if it wants to reverse the dramatic increase of people aged under 50 bein

Updated on: January 29,2024

Screening age needs to be lowered to combat colorectal cancer 'epidemic,' say researchers

by University of OtagoCredit: Pixabay/CC0 Public DomainNew Zealand needs to lower the screening age for colorectal cancer if it wants to reverse the dramatic increase of people aged under 50 bein

Updated on:January 29,2024

AI can predict the effectiveness of breast cancer chemotherapy

byUniversity of WaterlooCredit: Unsplash/CC0 Public DomainEngineers at the University of Waterloo have developed artificial intelligence (AI) technology to predict if women with breast cancer wo

Updated on: January 02,2024

AI can predict the effectiveness of breast cancer chemotherapy

byUniversity of WaterlooCredit: Unsplash/CC0 Public DomainEngineers at the University of Waterloo have developed artificial intelligence (AI) technology to predict if women with breast cancer wo

Updated on:January 02,2024

Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on: January 22,2024

Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on:January 22,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on: April 28,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on:April 28,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on: January 22,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on:January 22,2024

Some proteogenomic signatures linked to prostate cancer progression in patients with African and European ancestries

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainCertain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated wit

Updated on: April 28,2024

Some proteogenomic signatures linked to prostate cancer progression in patients with African and European ancestries

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainCertain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated wit

Updated on:April 28,2024