Scientists uncover key mechanism linking microtubules and chemotherapy, enhancing cancer drug efficacy

Updated on: March 17,2025 0

Scientists uncover key mechanism linking microtubules and chemotherapy, enhancing cancer drug efficacy

Updated on:March 17,2025 0

Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability

by Impact Journals LLCFGFR3-TACC3 fusion proteins. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28359FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in gliobl

Updated on: January 30,2024 10

Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability

by Impact Journals LLCFGFR3-TACC3 fusion proteins. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28359FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in gliobl

Updated on:January 30,2024 10

New strategy for treating the most aggressive type of brain cancer

by Maria Fernanda Ziegler,FAPESPCredit: CC0 Public DomainResearchers from the University of São Paulo (USP) in Brazil have developed a strategy for treating the most aggressive type of brain can

Updated on: April 09,2024 19

New strategy for treating the most aggressive type of brain cancer

by Maria Fernanda Ziegler,FAPESPCredit: CC0 Public DomainResearchers from the University of São Paulo (USP) in Brazil have developed a strategy for treating the most aggressive type of brain can

Updated on:April 09,2024 19

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell

Updated on: February 18,2024 18

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell

Updated on:February 18,2024 18

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on: January 30,2024 16

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on:January 30,2024 16

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C

Updated on: April 23,2024 13

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C

Updated on:April 23,2024 13

Research links development of childhood leukaemia to mistakes by the immune system

by University of LeedsA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaGenetic mutations that drive the

Updated on: July 02,2024 8

Research links development of childhood leukaemia to mistakes by the immune system

by University of LeedsA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaGenetic mutations that drive the

Updated on:July 02,2024 8

Finally, a potential new approach against KRAS-driven lung cancer

by CU Anschutz Medical CampusAlison Bauer, PhD, and colleagues identify MUC5AC as a new target in KRAS-driven lung cancer. Credit: University of Colorado Cancer CenterThe previous decade has seen

Updated on: March 21,2024 10

Finally, a potential new approach against KRAS-driven lung cancer

by CU Anschutz Medical CampusAlison Bauer, PhD, and colleagues identify MUC5AC as a new target in KRAS-driven lung cancer. Credit: University of Colorado Cancer CenterThe previous decade has seen

Updated on:March 21,2024 10

A new nutrition-screening tool for the oncologic population

byScience China PressVenn plots of three screening tools and malnutrition defined by PG-SGA. Malnutrition was defined as a PG-SGA score of ≥4. The malnutrition risk in MST was defined as an MST

Updated on: January 30,2024 20

A new nutrition-screening tool for the oncologic population

byScience China PressVenn plots of three screening tools and malnutrition defined by PG-SGA. Malnutrition was defined as a PG-SGA score of ≥4. The malnutrition risk in MST was defined as an MST

Updated on:January 30,2024 20

Study finds outcomes after stem cell transplant in elderly patients with AML have improved since 2000

by American Association for Cancer ResearchCredit: CC0 Public DomainAccording to astudypublished inClinical Cancer Research, among patients over 65 who received an allogeneic he

Updated on: March 30,2024 0

Study finds outcomes after stem cell transplant in elderly patients with AML have improved since 2000

by American Association for Cancer ResearchCredit: CC0 Public DomainAccording to astudypublished inClinical Cancer Research, among patients over 65 who received an allogeneic he

Updated on:March 30,2024 0

Balance of 'stop' and 'go' signaling could be key to cancer immunotherapy response

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainA crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by ca

Updated on: March 14,2024 10

Balance of 'stop' and 'go' signaling could be key to cancer immunotherapy response

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainA crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by ca

Updated on:March 14,2024 10

How a bereaved mom is helping researchers improve palliative care

by Erin Digitale,Stanford University Medical CenterJamila Hassan participated in research about end-of-life care for children after losing her son Omar to cancer in 2012. Credit: Courtesy of the

Updated on: January 04,2024 9

How a bereaved mom is helping researchers improve palliative care

by Erin Digitale,Stanford University Medical CenterJamila Hassan participated in research about end-of-life care for children after losing her son Omar to cancer in 2012. Credit: Courtesy of the

Updated on:January 04,2024 9